Research Profiles: LD-MS detects malaria parasite

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منابع مشابه

Potent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

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Potent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

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Malaria Parasite Diagnostics

NIMR is a Referral Centre for Evaluating Commercially Developed Diagnostic Kits — Designated by the Drugs Controller General of India Fig. 1: PCR based diagnosis One of the most pronounced problems in controlling the morbidity and mortality caused by malaria is the limited access to effective diagnosis and treatment in areas where malaria is endemic. The most widely used routine method of micro...

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Analysis of the active fraction of Iranian Naja naja oxiana snake venom on the metabolite profiles of the malaria parasite by 1HNMR in vitro

Objective(s): Malaria is an important parasitic disease with high morbidity and mortality in tropical areas. Resistance to most antimalarial drugs has encouraged the development of new drugs including natural products. Venom is a complex mixture of active pharmaceutical ingredients. The purpose of this study was to investigate the antimalarial activity of purified frac...

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Functional profiles of orphan membrane transporters in the life cycle of the malaria parasite

Assigning function to orphan membrane transport proteins and prioritizing candidates for detailed biochemical characterization remain fundamental challenges and are particularly important for medically relevant pathogens, such as malaria parasites. Here we present a comprehensive genetic analysis of 35 orphan transport proteins of Plasmodium berghei during its life cycle in mice and Anopheles m...

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ژورنال

عنوان ژورنال: Analytical Chemistry

سال: 2002

ISSN: 0003-2700,1520-6882

DOI: 10.1021/ac0220880